The pituitary gland is sometimes called the "master" gland of the endocrine system because it controls the functions of many of the other endocrine glands. The pituitary gland is no larger than a pea, and is located at the base of the brain. The gland is attached to the hypothalamus (a part of the brain that affects the pituitary gland) by nerve fibers and blood vessels. The pituitary gland itself consists of 2 major structures: Show
Functions of the pituitary glandEach lobe of the pituitary gland makes certain hormones. Anterior lobe
Posterior lobe
Oxytocin (to contract the uterus during childbirth and stimulate the release of milk during breastfeeding) Your pineal gland’s function and ability to release melatonin can be affected by the following conditions and situations:
Pineal gland tumorsPineal gland tumors are very rare, and there are several different types of them. They’re more likely to affect children and adults younger than 40. Pineal tumors aren't always cancer, but they still cause problems as they grow because they press against other parts of your brain. They can also block the normal flow of cerebrospinal fluid, which is the fluid that surrounds and cushions your brain. This blockage raises the pressure inside your skull, which is dangerous and requires treatment. Injuries that affect the pineal glandDamage to your pineal gland can cause it to work improperly. Approximately 30% to 50% of people who experience a traumatic brain injury (TBI) have issues with at least one endocrine gland in their brain, which includes the pineal gland and pituitary gland. A traumatic brain injury can happen when there is a blow to the head. The injury can be penetrating, like a gunshot wound, or a non-penetrating injury, like being struck in the head during a car accident. Concussions are the most common type of TBI. Pineal gland calcificationCalcification of the pineal gland is quite common. In fact, it’s so common that healthcare providers often use a calcified pineal gland as a landmark on x-rays to help identify different structures of the brain. Calcification happens when calcium builds up in body tissue, causing the tissue to harden. Your pineal gland tends to calcify as you age. While some calcification is normal, excessive calcification can prevent your pineal gland from functioning properly. Some studies have revealed that the degree of calcification of the pineal gland is higher in those affected by Alzheimer’s disease. There’s a loose link between pineal gland calcification and some migraine and cluster headaches. More studies need to be done to determine the exact effects of pineal gland calcification. What are the symptoms of pineal gland problems?If you have a pineal gland tumor, which are rare, you may experience the following symptoms: What are common tests to check the health of the pineal gland?Healthcare providers can look at your pineal gland with imaging tests, such as an MRI (magnetic resonance imaging) or a CT (computed tomography) scan. Providers use these imaging tests to help determine if you have a pineal tumor or cyst. Providers may also use X-rays to check for pineal gland calcification. Your provider can also check your melatonin levels with a blood test. How are pineal gland conditions treated?Pineal gland tumors may be treated with one or more of the following therapies:
If you have a condition that causes your pineal gland to secrete less-than-normal levels of melatonin, your provider may have you take an over-the-counter melatonin supplement. |